There are not many other natural regions offering so many possibilities for nature sports as Mikulov and its surroundings. The relief of the landscape is dominated by the Mikulov Hills with the limestone range of the Pálava Hills and the Milovice Forestland.

Especially the rocky Pálava attracts visitors and tourists with the abundance of Karst phenomena, and varied flora and fauna. Along the southern edge of the town there is the wide valley of the Včelínek stream, the largest right tributary to the Dyje. Another attraction is the connection to the Lednice-Valtice area and the Austrian part of the Pálava Hills.

The natural and landscape values of the Mikulov region is enhanced by the local climate, with the mildest winter and the highest number of sunny days of all regions of the Czech Republic. This makes it possible to spend free days and holidays in Mikulov and its natural surroundings all year round.